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Title: Chiral Discrimination of Tolterodine Tartrate by Modified Cyclodextrins
Authors: PavanKumar, V
SuryaNarayana, I
Nageswar, Y.V.D
RamaRao, K
Keywords: Tolterodine tartrate
Fluorescence intensity
Association constant
Issue Date: 2008
Publisher: Taylor & Francis
Citation: Journal of Carbohydrate Chemistry, 27:223–230p
Abstract: The chiral discrimination ability of two b-cyclodextrin derivatives (hosts) having a flexible pyrrolidinylidenesulfamido-appended moiety has been studied for the enantiomers of tolterodine tartrate (guest). Quenching of the fluorescence intensities of guests was observed in the presence of hosts. The S-enantiomer of the tolterodine tartrate was better recognized by these hosts. Enantioselectivity factors (a) and association constants (Ks) of the host–guest complexes were calculated.
ISSN: 1532-2327
Appears in Collections:Natural Product Chemistry(Org-I)

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